Welchol Oral Suspension Sachet (Colesevelam) Medication

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Drug Description


Welchol Oral Suspension Sachet (generically known as Colesevelam) is an oral medication used to lower cholesterol levels in the blood. It can be prescribed for people with high cholesterol who have not responded to other treatments or who are unable to tolerate other cholesterol-lowering medications. 

Colesevelam works by binding to bile acids in the intestine, preventing their reabsorption and promoting their elimination from the body. This can help reduce LDL cholesterol, total cholesterol, and blood sugar levels in individuals with certain conditions such as high cholesterol or type 2 diabetes. 

Use and Dosage 

Welchol Oral Suspension Sachet should be taken as directed by your healthcare professional. It is typically mixed with 4 to 8 ounces of water or other liquids and consumed with meals or as prescribed. Follow the instructions provided by your healthcare professional or refer to the medication’s label for specific dosing and administration guidelines. 

Start by emptying the entire contents of one packet into a glass or cup. Add 1 cup (8 ounces) of water, fruit juice, or diet soft drinks to the glass or cup. Stir well until the powder is fully dissolved in the liquid. Drink the mixture. Do not take Welchol Oral Suspension Sachet in its dry form. 

If you miss a dose, take it as soon as you remember. However, if it is close to the time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. 

Side Effects 

Common Side Effects 

  • Constipation 
  • Feeling weak or tired 
  • Flu symptoms 
  • Gas 
  • Headache 
  • Indigestion 
  • Muscle pain 
  • Nausea 
  • Runny nose 
  • Sore throat 
  • Upset stomach 
  • Vomiting 

Serious Side Effects 

  • Arm or leg weakness 
  • Blurred vision 
  • Confusion 
  • Eye pain or swelling 
  • Fast, irregular, or pounding heartbeats 
  • Feeling unsteady 
  • Fluttering in your chest 
  • High fever 
  • Lightheadedness 
  • Loss of coordination 
  • Passing out 
  • Profuse sweating, or tremors 
  • Seeing halos around lights 
  • Severe constipation 
  • Severe pain in your upper stomach spreading to your back 
  • Severe stomach pain 
  • Shortness of breath 
  • Slurred speech 
  • Sudden dizziness 
  • Sudden vision loss 
  • Trouble swallowing 
  • Trouble walking 
  • Tunnel vision 
  • Unusual bleeding or bruising 
  • Very stiff muscles 


  • Allergic reactions: Some individuals may be allergic to colesevelam or other ingredients in the medication. If you experience symptoms such as rash, itching, swelling, dizziness, or difficulty breathing, seek medical attention immediately. 
  • Gastrointestinal effects: Colesevelam may cause gastrointestinal side effects such as constipation, indigestion, abdominal pain, nausea, or vomiting. If these symptoms persist or worsen, consult your healthcare professional. 
  • Interactions with other medications: Welchol Oral Suspension may interact with other medications, including certain cholesterol-lowering drugs, thyroid medications, and certain vitamins. Inform your healthcare provider about all the medications you are taking to avoid potential interactions. 
  • Pregnancy and breastfeeding: The use of Welchol Oral Suspension during pregnancy or breastfeeding should be discussed with a healthcare professional. Weigh the potential benefits against any potential risks. 
  • Pre-existing medical conditions: Inform your healthcare professional about any pre-existing medical conditions you have, including a history of bowel obstruction or pancreatitis, as colesevelam may not be suitable for individuals with these conditions. 
  • Monitoring of lipid levels: Regular monitoring of lipid levels may be necessary while taking Welchol Oral Suspension to assess the effectiveness of the medication. 
  • Gallbladder disease: Welchol may increase the risk of developing gallstones or worsening symptoms in individuals with a history of gallbladder disease. Inform your healthcare professional if you have a history of gallbladder issues. 
  • Vitamin deficiencies: Colesevelam may interfere with the absorption of certain vitamins, particularly fat-soluble vitamins such as vitamins A, D, E, and K. Your healthcare provider may recommend monitoring vitamin levels or adjusting your vitamin supplementation if necessary. 
  • Diabetic patients: Welchol may affect blood sugar levels in individuals with diabetes. Close monitoring of blood glucose levels is important, and adjustments to diabetes medications may be necessary. Inform your healthcare professional if you have diabetes. 
  • Pediatric use: The safety and effectiveness of Welchol Oral Suspension in pediatric patients have not been established for certain conditions. Consult with a healthcare professional for appropriate use in children. 
  • Renal impairment: Welchol may accumulate in individuals with severe renal impairment. Dosing adjustments may be necessary for individuals with impaired kidney function. Inform your healthcare professional if you have kidney problems. 
  • Liver impairment: Welchol should be used with caution in individuals with severe liver impairment. The dosage may need to be adjusted. Discuss with your healthcare professional if you have liver issues.  

Additional information

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Quality Prescription Drugs has provided information from third parties intended to increase awareness and does not contain all the information about Welchol Oral Suspension Sachet (Colesevelam). Talk to your doctor or a qualified medical practitioner for medical attention, advice, or if you have any concerns about Welchol Oral Suspension Sachet (Colesevelam).