Zetia (Ezetimibe) Medication


Zetia (Ezetimibe)

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Table of contents:

Drug Description


Ezetimibe is indicated as an adjunct to a low-cholesterol/low-fat diet and exercise regimen to aid in the reduction of blood cholesterol levels. It can be used as monotherapy or in combination with other lipid-lowering agents, including “statins” or fibrates. Ezetimibe exerts its therapeutic effect by inhibiting intestinal absorption of cholesterol, resulting in decreased serum cholesterol levels. This pharmacological action is believed to confer a beneficial impact on cardiovascular outcomes, including reducing the risk of stroke and myocardial infarction. 

Uses and Dosage 

Zetia (Ezetimibe) functions by inhibiting the intestinal absorption of cholesterol, thereby reducing the amount of cholesterol that your body absorbs. You have to adhere to a cholesterol-lowering diet while taking this medication. 

The administration of this medication should be in accordance with the prescription of your doctor, usually once daily with or without food. The dose of this medication is determined by your medical condition and response to treatment. 

If you are concurrently taking a bile acid sequestrant (e.g., cholestyramine, colestipol), you should take ezetimibe at least 2 hours before or 4 hours after the administration of the bile acid sequestrant. The binding of these products to ezetimibe can impede the full absorption of the drug. 

Take this medication regularly to derive the maximum benefit from it. To aid in remembering, take it at the same time each day. 

Continue taking this medication even if you feel well. A majority of individuals with high cholesterol may not experience any symptoms. The full therapeutic effect of this medication may take up to 2 weeks to manifest. 

Side Effects 

Allergic Reaction

Seek emergency medical attention immediately in the event of an allergic reaction to Zetia (Ezetimibe), such as:  

  • Hives 
  • Difficulty breathing 
  • Swelling of the face, lips, tongue, or throat 

Severe Side Effects

Zetia may lead to the breakdown of muscle tissue, resulting in kidney failure. Promptly contact your physician if you experience:  

  • Unexplained muscle pain 
  • Tenderness or weakness especially when accompanied by fever 
  • Unusual tiredness 
  • Dark urine  

Adverse reactions to Zetia may be more probable in older adults.  

Common Side Effects

Common side effects of Zetia may include:  

  • Diarrhea 
  • Symptoms of the common cold such as: 
    • Stuffy nose 
    • Sneezing 
    • Sore throat 
  • Pain in an arm or leg 
  • Joint pain 
  • Muscle pain when used in combination with a statin 

This list of side effects is not comprehensive, and others may occur. consult your doctor for medical advice concerning side effects. 


Prior to taking Ezetimibe, inform your doctor or pharmacist if you have any known allergies to it or any other allergens. This medication may contain inactive ingredients that can trigger allergic reactions or other related problems. discuss any concerns with your pharmacist to obtain more detailed information. 

Before initiating the use of this medication, inform your doctor or pharmacist of your medical history, specifically any history of liver disease. 

Prior to undergoing any surgical procedure or dental treatment, inform your healthcare provider of all the products you use, including prescription medications, non-prescription medications, and herbal products. 

Additional information

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Quality Prescription Drugs has provided information from third parties intended to increase awareness and does not contain all the information about Zetia (Ezetimibe). Talk to your doctor or a qualified medical practitioner for medical attention, advice, or if you have any concerns about Zetia (Ezetimibe).