Colestid Granules (colestipol hydrochloride) Medication


Colestid Granules (colestipol hydrochloride)

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Colestid Granules is a prescribed medication used alongside a proper diet to reduce levels of low-density lipoprotein (LDL) “bad” cholesterol in patients with primary hypercholesterolemia (high cholesterol) when dietary measures are insufficient. 

Categorized as a bile acid sequestrant, Colestid functions by binding with bile acids in the intestines, resulting in a compound that is then eliminated in the stool. 

Uses and Dosage 

Before taking Colestid Granules and every time you refill your prescription, carefully read the accompanying medication guide and patient information leaflet. Should any queries arise, seek guidance from your doctor or pharmacist. 

The prescribed dosage of this medication is individualized according to the patient’s medical conditions and response to the treatment. 

To minimize the potential for side effects, your doctor may instruct you to initiate treatment at a lower dose and then gradually raise it. 

Typically, Colestid Granules are taken one to six times daily and should always be mixed in a liquid, like water or a preferred beverage. Alternatively, they can be incorporated into soups, cereals, or pulpy fruits but should never be ingested in dry form. 

To take this medication with beverages, follow these steps: 

  1. Pour the prescribed amount of Colestid Granules into a glass containing at least three ounces of water or your preferred beverage.  
    • Using a thicker or pulpy juice may help improve the texture. 
  2. Stir the mixture thoroughly until the medication is well distributed (granules will not dissolve in the liquid). 
  3. Rinse the glass with a small additional amount of your chosen beverage to ensure you consume all the medication. 

To enhance its intake, Colestid Granules can be combined with milk, hot or regular breakfast cereals, soups rich in fluids, and pulpy fruits such as crushed pineapple, pears, peaches, or fruit cocktails. 

To maximize the benefits of this medication, ensure to take it regularly at around the same time each day. 

Strictly follow your doctor’s instructions regarding the dosage and frequency of Colestipol Granules. Continue taking it even if you are feeling well, as many individuals with high cholesterol may not experience symptoms. 

Side Effects 

The potential adverse effects of Colestid Granules are outlined below. Promptly inform your doctor if any of these symptoms persist or worsen. 

Common Side Effects 

  • Stomach pain or heartburn 
  • Stomach cramps 
  • Gas 
  • Diarrhea 
  • Upset stomach or vomiting 
  • Constipation 

To alleviate constipation, consider increasing fluid intake, engaging in physical activity, or incorporating more fiber into your diet. Consult your doctor regarding the use of stool softeners or laxatives if needed. 

Serious Side Effects 

  • Severe abdominal pain 
  • Severe constipation 
  • Difficulty swallowing 
  • Unexplained bruising or bleeding 

Contact your doctor immediately and ask for medical help if any of the severe symptoms above occur. 

Allergic Reactions 

In rare cases, Colestid Granules may trigger a severe allergic response. Immediate medical help is needed if you observe signs of an allergic reaction, such as: 

  • Rash 
  • Hives 
  • Itching 
  • Skin redness, swelling, blistering, or peeling with or without fever 
  • Wheezing 
  • Chest or throat tightness 
  • Breathing, swallowing, or speaking difficulties 
  • Unusual hoarseness 
  • Swelling of the mouth, face, lips, tongue, or throat 

This list does not cover all side effects of Colestid Granules. Report any other symptoms you may experience to your doctor. 


Before starting treatment with Colestid Granules, inform your doctor if you have any known allergies, particularly to colestipol or any of its inactive components. 

Seek advice from your doctor before taking Colestid Granules if you have a history of: 

  • Constipation 
  • Hemorrhoids 
  • Kidney disease 

Colestid Granules may interact with blood thinners (e.g., warfarin), mycophenolate, and raloxifene. To minimize potential interactions, disclose all your current medications, including prescriptions, over-the-counter drugs, vitamins, and herbal products, to your healthcare provider. 

Colestid can reduce the absorption of other medications. Follow your doctor’s instructions for taking your other medicines, typically at least 1 hour before or 4 to 6 hours after taking Colestid Granules.  

Your doctor may recommend a multivitamin supplement during the treatment with Colestid Granules as it can affect the absorption of specific nutrients, including folic acid and fat-soluble vitamins like A, D, E, and K. 

Notify your doctor about your pregnancy status or intentions. A thorough discussion regarding the pros and cons of employing Colestid Granules while pregnant will be necessary. 

Colestipol is not likely to be passed in breast milk. However, because it can affect the absorption of specific nutrients, it’s advisable to consult your doctor before breastfeeding. 

Additional information

Generic name:

colestipol hydrochloride





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Quality Prescription Drugs has provided information from third parties intended to increase awareness and does not contain all the information about Colestid Granules (colestipol hydrochloride). Talk to your doctor or a qualified medical practitioner for medical attention, advice, or if you have any concerns about Colestid Granules (colestipol hydrochloride).