Dexilant (Dexlansoprazole) Medication


Dexilant (Dexlansoprazole)

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What is DEXILANT (dexlansoprazole)?

Dexilant is an oral medication called a proton pump inhibitor (PPI), which reduces the amount of acid in your stomach. It is prescribed for the management of heartburn and other symptomscaused by gastroesophageal reflux disease (GERD).

This medication is effective in promoting the healing of erosive esophagitis, a condition characterized by damage to the esophagus due to the corrosive effects of stomach acid.

By reducing the production of stomach acid and neutralizing any excess acid present in the digestive tract, Dexilant helps to alleviate the discomfort and irritation associated with these conditions and promotes healing of the damaged tissue.

DEXILANT (dexlansoprazole) Indications and Uses

  • Healing of Erosive Esophagitis Treatment
    • DEXILANT is indicated for healing all grades of erosive esophagitis (EE) for up to 8 weeks.
  • Maintenance of Healed Erosive Esophagitis
    • Dexilant is indicated to maintain healing of EE and relief of heartburn for up to 6 months.
  • Symptomatic Non-Erosive Gastroesophageal Reflux Disease
    • Dexilant is indicated for the treatment of heartburn associated with symptomatic non-erosive GERDfor 4 weeks.


DEXILANT (dexlansoprazole) Dosing

  • Healing of EE
    • 60 mg once daily up to 8 weeks
  • Maintenance of Healed EE and Relief of Heartburn

30 mg once daily (controlled studies did not extend beyond 6 months in adults and 16 weeks in patients 12 to 17 years of age)

  • Symptomatic Non-Erosive GERD
    • One 30 mg once dailyfor 4 weeks

Side Effects of DEXILANT (dexlansoprazole)

The most commonly reported side effects of Dexilantwere:

  • Diarrhea
  • Abdominal pain
  • Nausea
  • Upper respiratory tract infection
  • Vomiting
  • Flatulence

This is not a complete list of side effects of Dexilant. Consult your doctor if you experienced any uncommon side effects.


If you develop any of the following, contact your doctor right away:

  • Symptoms of low magnesium blood level (such as muscle spasms, irregular heartbeat, seizures)
  • Signs of lupus (such as rash on nose and cheeks, new or worsening joint pain)
  • Persistent diarrhea, abdominal or stomach pain/cramping, blood/mucus in your stool



Get immediate medical attention if you experience allergic reactions like:

  • Hives
  • Trouble breathing
  • Swelling of your face, lips, tongue, or neck

DEXILANT (dexlansoprazole) Warnings and Precautions

  • Gastric malignancy
    Symptomatic response with Dexilant does not eliminate the presence of gastric malignancy.
  • Clostridium Difficile Associated Diarrhea
    Dexilant may increase your risk of getting severe diarrhea, which may be caused by an infection (Clostridium difficile) in your intestines. Patients should use the lowest dose and shortest duration of PPI therapy appropriate for the condition being treated.
  • Bone fracture
    People who take multiple daily doses of proton pump inhibitor medicines for a long period of time (a year or longer) may have an increased risk of fractures of the hip, wrist or spine. You should take Dexilant exactly as prescribed, at the lowest dose possible for your treatment and for the shortest time needed.
  • Hypomagnesemia (lower than normal amount of magnesium in the blood)
    This has been reported rarely, in most cases after a year of PPI therapy. In most patients, treatment of hypomagnesemia required magnesium replacement and discontinuation of the medication.
  • Concomitant use with methotrexate
    Use of a PPI with methotrexate (primarily at high dose) may elevate and prolong serum levels of methotrexate and/or its metabolite, possible leading to toxicities.

Inform your physician or pharmacist of any known allergies prior to initiating treatment with dexlansoprazole, including those to similar medications such as lansoprazole and omeprazole. Disclose any pre-existing medical conditions, specifically those related to the liver and lupus.

DEXILANT (dexlansoprazole) Form and Strengths

You can order Dexilant (dexlansoprazole) medication in the following forms and strengths:

  • Dexilant delayed-released capsule:
    • 30mg
    • 60mg
  • Dexlansoprazole modified-release capsule:
    • 30mg
    • 60mg

Frequently Asked Questions

How should I take Dexilant?

  • Take Dexilant exactly as prescribed by your doctor
  • Do not change your dose or stop taking Dexilant without consulting your doctor first
  • Dexilant may be taken with or without food
  • Dexilant capsules should be swallowed whole, not chewed; if you have trouble swallowing capsules whole, open the capsule and sprinkle the contents on a tablespoon of applesauce

Are there any drug interactions I should be aware of while taking Dexilant?

Dexilant has the potential to interact with the following drugs:

  • Atazanavir
  • Drugs with pH-dependent absorption (eg, digoxin, ketoconazole)
  • Warfarin
  • Tacrolimus
  • Methotrexate

It is important to let your doctor know if you are taking any of these medications prior to starting Dexilant.



Additional information

Generic name:



Delayed Release Capsule, Delayed Release capsule, Modified Release Capsule


30mg, 60mg

Quantities Available:

90, 100

Quality Prescription Drugs has provided information from third parties intended to increase awareness and does not contain all the information about Dexilant (Dexlansoprazole). Talk to your doctor or a qualified medical practitioner for medical attention, advice, or if you have any concerns about Dexilant (Dexlansoprazole).